Precision Immunology
and Microbiome Medicine
Laboratory
We use multi-omic analysis to make observations in human studies and investigate mechanisms in the hope of bringing back bet
Learn MoreWe study the impact of microbial exposures on immune health and immunomodulatory therapies.
Learn MoreWe investigate a broad range of healthy states and diseases where immune interventions aim at promoting immunity or tolerance
Learn MoreJoin our vibrant team of researchers or find out how to contribute to our research.
Learn More
Find fresh news
about the lab.
Our team is bold, diverse and curious. Meet our members.
Learn MoreApproach
Mission
Research
Opportunities
News
Team
Approach
Overview
Our lab uses a "From bedside to bench, and back to the patient" research approach to focus our work on biological insights that directly enhance patient care and treatment.
Approach
Stage 1 Research. Human-centric Insight Discovery Studies
Reverse translational human research and precision Immunology: We study human immune specimens from patients using multiomic analysis and systems approach. We use data generated from CyTOF, CITE-Seq, mass spectrometry, multiplexed serology, whole metagenome shotgun sequencing and more.
Approach
Stage 2 Research. Model-centric Mechanistic Studies
We use a broad range of cell and molecular and models to validate observations made in human studies
Approach
Stage 3 Research. Precision Medicine Therapeutics Development
We help design innovative therapeutic strategies that involve patient tailored microbiome medicine to support targeted immunomodulation.
Mission
Scientific Mission
Our goal is to explore how microbial exposures influence human immune responses in health and disease. We do this by investigating the impact of the microbiome, environmental microbes, and pathogens on the immune system. Ultimately, we aim to improve patient care with precision immunomodulatory treatments and advance microbiome-based medicine.
- Immune Setpoint: Understanding how the unique microbiome and environmental microbial exposures
shape a spectrum of immune configurations that differ across individuals. - Precision Immunology: Understanding how patients’ immune setpoints influence patient response
to immunomodulatory interventions. - Microbiome Medicine: Harnessing the power of the microbiome to improve immune health and
immunomodulation therapy responsiveness.
Mission
About Us
Mission
Social Awareness
Our lab is committed to fostering an inclusive and supportive environment through ongoing allyship learning. We engage in discussions about the challenges faced by underrepresented groups and those who encounter systemic barriers in science. These efforts equip us with the knowledge to be effective allies, fostering a collaborative and welcoming workspace for everyone.
Mission
Community Service
Our lab is committed to advancing human well-being while preserving the fragile ecosystem we are part of. We embrace sustainable research that benefits all, especially populations most vulnerable to natural and human-made health hazards. Recognizing the disproportionate challenges these populations face, we dedicate our work to developing large-scale, low-cost precision therapies to make treatments accessible to everyone.
Research
Our research investigates health at different stages of life and a broad spectrum of clinical settings that involve therapeutic and preventative immune interventions.
Maintenance of Immune Health
Defining immune health and the impact of microbe exposures on the immune systems, at various stages of human life and in various environments.
Pediatric Health
Adult Health
Aging
Space Health
Induction of Immune Activation
Investigating how microbial exposures affect responsiveness to treatments that aim at inducing immune responses.
Cancer immunotherapy
Vaccine immunity
Induction of Immune Tolerance
Investigating how microbial exposures affect responsiveness to treatments that aim at inducing immune tolerance.
Immunosuppression in the context autoimmunity
Tolerization of organ transplants
Research
Defining immune health and the impact of microbe exposures on the immune systems, at various stages of human life and in various environments.
Maintenance of Immune Health
Pediatric Health
Adult Health
Aging
Space Health
Projects
Research
Investigating how microbial exposures affect responsiveness to treatments that aim at inducing immune responses.
Induction of Immune Activation
Cancer immunotherapy
Vaccine immunity
Projects
Research
Investigating how microbial exposures affect responsiveness to treatments that aim at inducing immune tolerance.
Induction of Immune Tolerance
Immunosuppression in the context autoimmunity
Tolerization of organ transplants
Projects
Opportunities
Open Positions
Join our vibrant team of researchers or find out how to contribute to our research and help our biomedical community understand the dialogue between the microbiome and the immune system, and how we can harness it to develop novel innovative immunomodulation therapy strategies.
Opportunities
Contact
We’re always open to discussing potential collaborations, inquiries about our work, or any opportunities to contribute to our research. If you have any questions or would like more information about our research, please fill out the form below and someone from our team will respond shortly.
News
News in the Lab
News
Lab Members in the News
Team
Members
Francine Baker
PhD Student (IGG)
Josie King
Graduate Rotation Student (PGG)
Kristen Krip
Lab Manager/Research Specialist
Kelvin Koser
Computational Scientist
Joel Babdor
Principal Investigator
Team
Alumni
Isabel Boix
Undergraduate Research Assistant
David Wu
Graduate Rotation Student (MSTP/GCB)
Skyler Hoang
Research Specialist